Use of a Recombinant Vaccinia Virus Expressing Interferon Gamma for Post-Exposure Protection against Vaccinia and Ectromelia Viruses

Susan A. Holechek; Karen L. Denzler; Michael C. Heck; Jill Schriewer; R. Mark Buller; Fatema A. Legrand; Paulo H. Verardi; Leslie A. Jones; Tilahun Yilma; Bertram L. Jacobs

doi:10.1371/journal.pone.0077879

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Open Access

Peer-reviewed

Research Article

Use of a Recombinant Vaccinia Virus Expressing Interferon Gamma for Post-Exposure Protection against Vaccinia and Ectromelia Viruses

Susan A. Holechek,

Affiliation Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America
⨯
Karen L. Denzler,

Affiliation Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America
⨯
Michael C. Heck,

Affiliation Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America
⨯
Jill Schriewer,

Affiliation Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States of America
⨯
R. Mark Buller,

Affiliation Department of Molecular Microbiology and Immunology, Saint Louis University Health Sciences Center, St. Louis, Missouri, United States of America
⨯
Fatema A. Legrand,

Affiliation International Laboratory of Molecular Biology for Tropical Disease Agents, School of Veterinary Medicine, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America
⨯
Paulo H. Verardi,

Affiliation Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, United States of America
⨯
Leslie A. Jones,

Affiliation International Laboratory of Molecular Biology for Tropical Disease Agents, School of Veterinary Medicine, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America
⨯
Tilahun Yilma,

Affiliation International Laboratory of Molecular Biology for Tropical Disease Agents, School of Veterinary Medicine, Department of Medical Microbiology and Immunology, School of Medicine, University of California, Davis, California, United States of America
⨯
Bertram L. Jacobs

* E-mail: bjacobs@asu.edu

Affiliation Center for Infectious Diseases and Vaccinology, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America
⨯

Use of a Recombinant Vaccinia Virus Expressing Interferon Gamma for Post-Exposure Protection against Vaccinia and Ectromelia Viruses

Susan A. Holechek,
Karen L. Denzler,
Michael C. Heck,
Jill Schriewer,
R. Mark Buller,
Fatema A. Legrand,
Paulo H. Verardi,
Leslie A. Jones,
Tilahun Yilma,
Bertram L. Jacobs

Published: October 17, 2013
https://doi.org/10.1371/journal.pone.0077879

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