Aliskiren Attenuates Steatohepatitis and Increases Turnover of Hepatic Fat in Mice Fed with a Methionine and Choline Deficient Diet

Kuei-Chuan Lee; Che-Chang Chan; Ying-Ying Yang; Yun-Cheng Hsieh; Yi-Hsiang Huang; Han-Chieh Lin

doi:10.1371/journal.pone.0077817

Loading metrics

Open Access

Peer-reviewed

Research Article

Aliskiren Attenuates Steatohepatitis and Increases Turnover of Hepatic Fat in Mice Fed with a Methionine and Choline Deficient Diet

Kuei-Chuan Lee,

Affiliations Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
⨯
Che-Chang Chan,

Affiliations Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
⨯
Ying-Ying Yang,

Affiliations Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Division of General Medicine, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
⨯
Yun-Cheng Hsieh,

Affiliations Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
⨯
Yi-Hsiang Huang ,

* E-mail: yhhuang@vghtpe.gov.tw (YHH); hclin@vghtpe.gov.tw (HCL)

Affiliations Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, Institute of Clinical Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
⨯
Han-Chieh Lin

* E-mail: yhhuang@vghtpe.gov.tw (YHH); hclin@vghtpe.gov.tw (HCL)

Affiliations Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan
⨯

Aliskiren Attenuates Steatohepatitis and Increases Turnover of Hepatic Fat in Mice Fed with a Methionine and Choline Deficient Diet

Kuei-Chuan Lee,
Che-Chang Chan,
Ying-Ying Yang,
Yun-Cheng Hsieh,
Yi-Hsiang Huang,
Han-Chieh Lin

Published: October 21, 2013
https://doi.org/10.1371/journal.pone.0077817

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Fatty liver
Is the Subject Area "Fatty liver" applicable to this article?

Thanks for your feedback.
Steatosis
Is the Subject Area "Steatosis" applicable to this article?

Thanks for your feedback.
Insulin
Is the Subject Area "Insulin" applicable to this article?

Thanks for your feedback.
Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.
Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Hepatocytes
Is the Subject Area "Hepatocytes" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.