Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight from Xenon Trapping and Statistical Coupling Analysis

Open Access

Peer-reviewed

Research Article

Ajay Singh Tanwar ,

Contributed equally to this work with: Ajay Singh Tanwar, Venuka Durani Goyal

Affiliation Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, India
⨯
Venuka Durani Goyal ,

Contributed equally to this work with: Ajay Singh Tanwar, Venuka Durani Goyal

Affiliation Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, India
⨯
Deepanshu Choudhary,

Affiliation Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, India
⨯
Santosh Panjikar,

Affiliations Australian Synchrotron, Clayton, Australia, Department of Biochemistry and Molecular Biology, Monash University, Victoria, Australia
⨯
Ruchi Anand

* E-mail: ruchi@chem.iitb.ac.in

Affiliation Department of Chemistry, Indian Institute of Technology Bombay, Mumbai, India
⨯

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Xenon
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Crystal structure
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Protein structure
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Ammonia
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Sequence alignment
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Protein domains
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Allosteric regulation
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Multiple alignment calculation
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