Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

Julia Diegelmann; Darina Czamara; Emmanuelle Le Bras; Eva Zimmermann; Torsten Olszak; Andrea Bedynek; Burkhard Göke; Andre Franke; Jürgen Glas; Stephan Brand

doi:10.1371/journal.pone.0077773

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Peer-reviewed

Research Article

Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

Julia Diegelmann ,

Contributed equally to this work with: Julia Diegelmann, Darina Czamara, Jürgen Glas, Stephan Brand

Affiliations Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany, Department of Preventive Dentistry and Periodontology, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Darina Czamara ,

Contributed equally to this work with: Julia Diegelmann, Darina Czamara, Jürgen Glas, Stephan Brand

Affiliations Max-Planck-Institute for Psychiatry, Munich, Germany, Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
⨯
Emmanuelle Le Bras,

Affiliation Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Eva Zimmermann,

Affiliation Department of Preventive Dentistry and Periodontology, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Torsten Olszak,

Affiliations Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Andrea Bedynek,

Affiliation Department of Clinical Chemistry, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Burkhard Göke,

Affiliation Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯
Andre Franke,

Affiliation Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany
⨯
Jürgen Glas ,

Contributed equally to this work with: Julia Diegelmann, Darina Czamara, Jürgen Glas, Stephan Brand

Affiliations Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany, Department of Preventive Dentistry and Periodontology, Ludwig-Maximilians-University (LMU), Munich, Germany, Department of Human Genetics, Rheinisch-Westfälische Technische Hochschule (RWTH), Aachen, Germany
⨯
Stephan Brand

Contributed equally to this work with: Julia Diegelmann, Darina Czamara, Jürgen Glas, Stephan Brand

* E-mail: stephan.brand@med.uni-muenchen.de

Affiliation Department of Medicine II - Grosshadern, Ludwig-Maximilians-University (LMU), Munich, Germany
⨯

Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

Julia Diegelmann,
Darina Czamara,
Emmanuelle Le Bras,
Eva Zimmermann,
Torsten Olszak,
Andrea Bedynek,
Burkhard Göke,
Andre Franke,
Jürgen Glas,
Stephan Brand

Published: November 5, 2013
https://doi.org/10.1371/journal.pone.0077773

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