Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition

Muthulakshmi Muthuswami; Vignesh Ramesh; Saikat Banerjee; Soundara Viveka Thangaraj; Jayaprakash Periasamy; Divya Bhaskar Rao; Georgina D. Barnabas; Swetha Raghavan; Kumaresan Ganesan

doi:10.1371/journal.pone.0077553

Loading metrics

Open Access

Peer-reviewed

Research Article

Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition

Muthulakshmi Muthuswami ,

Contributed equally to this work with: Muthulakshmi Muthuswami, Vignesh Ramesh, Saikat Banerjee

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Vignesh Ramesh ,

Contributed equally to this work with: Muthulakshmi Muthuswami, Vignesh Ramesh, Saikat Banerjee

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Saikat Banerjee ,

Contributed equally to this work with: Muthulakshmi Muthuswami, Vignesh Ramesh, Saikat Banerjee

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Soundara Viveka Thangaraj,

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Jayaprakash Periasamy,

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Divya Bhaskar Rao,

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Georgina D. Barnabas,

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯
Swetha Raghavan,

Affiliation Department of Biotechnology, Indian Institute of Technology Madras, Chenna, India
⨯
Kumaresan Ganesan

* E-mail: kumar@oncocellomics.org

Affiliation Cancer Genetics Laboratory, Department of Genetics, Centre for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, India
⨯

Breast Tumors with Elevated Expression of 1q Candidate Genes Confer Poor Clinical Outcome and Sensitivity to Ras/PI3K Inhibition

Muthulakshmi Muthuswami,
Vignesh Ramesh,
Saikat Banerjee,
Soundara Viveka Thangaraj,
Jayaprakash Periasamy,
Divya Bhaskar Rao,
Georgina D. Barnabas,
Swetha Raghavan,
Kumaresan Ganesan

Published: October 17, 2013
https://doi.org/10.1371/journal.pone.0077553

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Breast tumors
Is the Subject Area "Breast tumors" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Ras signaling
Is the Subject Area "Ras signaling" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Regulator genes
Is the Subject Area "Regulator genes" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.