Chlamydia pneumoniae Infection in Mice Induces Chronic Lung Inflammation, iBALT Formation, and Fibrosis

Madhulika Jupelli; Kenichi Shimada; Norika Chiba; Anatoly Slepenkin; Randa Alsabeh; Heather D. Jones; Ellena Peterson; Shuang Chen; Moshe Arditi; Timothy R. Crother

doi:10.1371/journal.pone.0077447

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Open Access

Peer-reviewed

Research Article

Chlamydia pneumoniae Infection in Mice Induces Chronic Lung Inflammation, iBALT Formation, and Fibrosis

Madhulika Jupelli,

Current address: Division of Infectious Diseases, The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California, United States of America

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Kenichi Shimada,

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Norika Chiba,

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Anatoly Slepenkin,

Affiliation Department of Pathology, University of California Irvine, Irvine, California, United States of America
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Randa Alsabeh,

Affiliation Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, University of California Los Angeles, Los Angeles, California, United States of America
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Heather D. Jones,

Affiliation Division of Pulmonary and Critical Care Medicine, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Ellena Peterson,

Affiliation Department of Pathology, University of California Irvine, Irvine, California, United States of America
⨯
Shuang Chen,

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Moshe Arditi ,

Contributed equally to this work with: Moshe Arditi, Timothy R. Crother

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯
Timothy R. Crother

Contributed equally to this work with: Moshe Arditi, Timothy R. Crother

* E-mail: timothy.crother@cshs.org

Affiliation Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
⨯

Chlamydia pneumoniae Infection in Mice Induces Chronic Lung Inflammation, iBALT Formation, and Fibrosis

Madhulika Jupelli,
Kenichi Shimada,
Norika Chiba,
Anatoly Slepenkin,
Randa Alsabeh,
Heather D. Jones,
Ellena Peterson,
Shuang Chen,
Moshe Arditi,
Timothy R. Crother

Published: October 25, 2013
https://doi.org/10.1371/journal.pone.0077447

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