Alternative 5’ Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1

Marcel Kramer; Christoph Sponholz; Monique Slaba; Bianka Wissuwa; Ralf A. Claus; Uwe Menzel; Klaus Huse; Matthias Platzer; Michael Bauer

doi:10.1371/journal.pone.0077224

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Open Access

Peer-reviewed

Research Article

Alternative 5’ Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1

Marcel Kramer ,

* E-mail: Marcel.Kramer@med.uni-jena.de

Affiliations Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany, Genome Analysis, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena, Germany
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Christoph Sponholz,

Affiliations Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany, Genome Analysis, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena, Germany, Department of Anaesthesiology and Intensive Care Therapy, Jena University Hospital, Jena, Germany
⨯
Monique Slaba,

Affiliation Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany
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Bianka Wissuwa,

Affiliation Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany
⨯
Ralf A. Claus,

Affiliation Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany
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Uwe Menzel,

Affiliation Hans Knöll Institute for Natural Product Research and Infection Biology, Leibniz Institute, Jena, Germany
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Klaus Huse,

Affiliation Genome Analysis, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena, Germany
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Matthias Platzer,

Affiliation Genome Analysis, Leibniz Institute for Age Research - Fritz Lipmann Institute, Jena, Germany
⨯
Michael Bauer

Affiliations Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany, Department of Anaesthesiology and Intensive Care Therapy, Jena University Hospital, Jena, Germany
⨯

Alternative 5’ Untranslated Regions Are Involved in Expression Regulation of Human Heme Oxygenase-1

Marcel Kramer,
Christoph Sponholz,
Monique Slaba,
Bianka Wissuwa,
Ralf A. Claus,
Uwe Menzel,
Klaus Huse,
Matthias Platzer,
Michael Bauer

Published: October 2, 2013
https://doi.org/10.1371/journal.pone.0077224

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Alternative splicing
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5' UTR
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Polymerase chain reaction
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Gene expression
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Heme
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Luciferase
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Transfection
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Messenger RNA
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