The Involvement of PI3K-Mediated and L-VGCC-Gated Transient Ca2+ Influx in 17β-Estradiol-Mediated Protection of Retinal Cells from H2O2-Induced Apoptosis with Ca2+ Overload

Open Access

Peer-reviewed

Research Article

The Involvement of PI3K-Mediated and L-VGCC-Gated Transient Ca²⁺ Influx in 17β-Estradiol-Mediated Protection of Retinal Cells from H₂O₂-Induced Apoptosis with Ca²⁺ Overload

Yan Feng,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Baoying Wang,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Fangying Du,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Hongbo Li,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Shaolan Wang,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Chenghu Hu,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Chunhui Zhu,

Affiliation Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Xiaorui Yu

* E-mail: xiaoruiy@mail.xjtu.edu.cn

Affiliations Department of Genetics and Molecular Biology, School of Medicine, Xi’an Jiaotong University, Xi’an, China, Key Laboratory of Environment-and-Gene Related Diseases of the Ministry of Education, School of Medicine, Xi’an Jiaotong University, Xi’an, China
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Apoptosis
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Cell viability testing
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Retina
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Central nervous system
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Estrogens
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Homeostasis
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MTT assay
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Cell staining
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