Inhibition of Intestinal Epithelial Apoptosis Improves Survival in a Murine Model of Radiation Combined Injury

Enjae Jung; Erin E. Perrone; Pavan Brahmamdan; Jacquelyn S. McDonough; Ann M. Leathersich; Jessica A. Dominguez; Andrew T. Clark; Amy C. Fox; W. Michael Dunne; Richard S. Hotchkiss; Craig M. Coopersmith

doi:10.1371/journal.pone.0077203

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Peer-reviewed

Research Article

Inhibition of Intestinal Epithelial Apoptosis Improves Survival in a Murine Model of Radiation Combined Injury

Enjae Jung,

Affiliation Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Erin E. Perrone,

Affiliation Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Pavan Brahmamdan,

Affiliation Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Jacquelyn S. McDonough,

Affiliation Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Ann M. Leathersich,

Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Jessica A. Dominguez,

Affiliation Department of Basic Sciences, Bastyr University California, San Diego, California, United States of America
⨯
Andrew T. Clark,

Affiliation Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Amy C. Fox,

Affiliation Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
W. Michael Dunne,

Affiliation Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Richard S. Hotchkiss,

Affiliation Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯
Craig M. Coopersmith

* E-mail: cmcoop3@emory.edu

Affiliation The Emory Center for Critical Care and Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, United States of America
⨯

Inhibition of Intestinal Epithelial Apoptosis Improves Survival in a Murine Model of Radiation Combined Injury

Enjae Jung,
Erin E. Perrone,
Pavan Brahmamdan,
Jacquelyn S. McDonough,
Ann M. Leathersich,
Jessica A. Dominguez,
Andrew T. Clark,
Amy C. Fox,
W. Michael Dunne,
Richard S. Hotchkiss

Published: October 28, 2013
https://doi.org/10.1371/journal.pone.0077203

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