Digitoflavone Inhibits IκBα Kinase and Enhances Apoptosis Induced by TNFα through Downregulation of Expression of Nuclear Factor κB-Regulated Gene Products in Human Pancreatic Cancer Cells

Xueting Cai; Wuguang Lu; Yang Yang; Jie Yang; Juan Ye; Zhenhua Gu; Chunping Hu; Xiaoning Wang; Peng Cao

doi:10.1371/journal.pone.0077126

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Peer-reviewed

Research Article

Digitoflavone Inhibits IκBα Kinase and Enhances Apoptosis Induced by TNFα through Downregulation of Expression of Nuclear Factor κB-Regulated Gene Products in Human Pancreatic Cancer Cells

Xueting Cai,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Wuguang Lu,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Yang Yang,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Jie Yang,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Juan Ye,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Zhenhua Gu,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Chunping Hu,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Xiaoning Wang,

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯
Peng Cao

* E-mail: pcao79@yahoo.com

Affiliations Jiangsu Branch of China Academy of Chinese Medical Sciences, Nanjing, China, Laboratory of Cellular and Molecular Biology, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
⨯

Digitoflavone Inhibits IκBα Kinase and Enhances Apoptosis Induced by TNFα through Downregulation of Expression of Nuclear Factor κB-Regulated Gene Products in Human Pancreatic Cancer Cells

Xueting Cai,
Wuguang Lu,
Yang Yang,
Jie Yang,
Juan Ye,
Zhenhua Gu,
Chunping Hu,
Xiaoning Wang,
Peng Cao

Published: October 11, 2013
https://doi.org/10.1371/journal.pone.0077126

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