Bradykinin Inhibits Oxidative Stress-Induced Cardiomyocytes Senescence via Regulating Redox State

Ruolan Dong; Xizhen Xu; Geng Li; Wenjing Feng; Gang Zhao; Junjie Zhao; Dao Wen Wang; Ling Tu

doi:10.1371/journal.pone.0077034

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Peer-reviewed

Research Article

Bradykinin Inhibits Oxidative Stress-Induced Cardiomyocytes Senescence via Regulating Redox State

Ruolan Dong ,

Contributed equally to this work with: Ruolan Dong, Xizhen Xu

Affiliation Department of Geriatric Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Xizhen Xu ,

Contributed equally to this work with: Ruolan Dong, Xizhen Xu

Affiliation The Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Geng Li,

Affiliation Department of Geriatric Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Wenjing Feng,

Affiliation Department of Geriatric Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Gang Zhao,

Affiliation The Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Junjie Zhao,

Affiliation Department of Geriatric Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Dao Wen Wang,

Affiliation The Institute of Hypertension and Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯
Ling Tu

* E-mail: proftu@tom.com

Affiliation Department of Geriatric Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China
⨯

Bradykinin Inhibits Oxidative Stress-Induced Cardiomyocytes Senescence via Regulating Redox State

Ruolan Dong,
Xizhen Xu,
Geng Li,
Wenjing Feng,
Gang Zhao,
Junjie Zhao,
Dao Wen Wang,
Ling Tu

Published: October 25, 2013
https://doi.org/10.1371/journal.pone.0077034

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DNA damage
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Cardiomyocytes
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Receptor antagonist therapy
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