Characterization of Lung Cancer by Amide Proton Transfer (APT) Imaging: An In-Vivo Study in an Orthotopic Mouse Model

Osamu Togao; Chase W. Kessinger; Gang Huang; Todd C. Soesbe; Koji Sagiyama; Ivan Dimitrov; A. Dean Sherry; Jinming Gao; Masaya Takahashi

doi:10.1371/journal.pone.0077019

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Peer-reviewed

Research Article

Characterization of Lung Cancer by Amide Proton Transfer (APT) Imaging: An In-Vivo Study in an Orthotopic Mouse Model

Osamu Togao,

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Chase W. Kessinger,

Affiliation Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Gang Huang,

Affiliation Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Todd C. Soesbe,

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Koji Sagiyama,

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Ivan Dimitrov,

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
A. Dean Sherry,

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Jinming Gao,

Affiliation Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Masaya Takahashi

* E-mail: masaya.takahashi@utsouthwestern.edu

Affiliation Advanced Imaging Research Center, Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, United States of America
⨯

Characterization of Lung Cancer by Amide Proton Transfer (APT) Imaging: An In-Vivo Study in an Orthotopic Mouse Model

Osamu Togao,
Chase W. Kessinger,
Gang Huang,
Todd C. Soesbe,
Koji Sagiyama,
Ivan Dimitrov,
A. Dean Sherry,
Jinming Gao,
Masaya Takahashi

Published: October 15, 2013
https://doi.org/10.1371/journal.pone.0077019

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Lung and intrathoracic tumors
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Secondary lung tumors
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Non-small cell lung cancer
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