Deep Bisulfite Sequencing of Aberrantly Methylated Loci in a Patient with Multiple Methylation Defects

Jasmin Beygo; Ole Ammerpohl; Daniela Gritzan; Melanie Heitmann; Katrin Rademacher; Julia Richter; Almuth Caliebe; Reiner Siebert; Bernhard Horsthemke; Karin Buiting

doi:10.1371/journal.pone.0076953

Loading metrics

Open Access

Peer-reviewed

Research Article

Deep Bisulfite Sequencing of Aberrantly Methylated Loci in a Patient with Multiple Methylation Defects

Jasmin Beygo ,

Contributed equally to this work with: Jasmin Beygo, Ole Ammerpohl

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯
Ole Ammerpohl ,

Contributed equally to this work with: Jasmin Beygo, Ole Ammerpohl

Affiliation Institute of Human Genetics, Christian-Albrechts-University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Daniela Gritzan,

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯
Melanie Heitmann,

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯
Katrin Rademacher,

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯
Julia Richter,

Affiliation Institute of Human Genetics, Christian-Albrechts-University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Almuth Caliebe,

Affiliation Institute of Human Genetics, Christian-Albrechts-University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Reiner Siebert,

Affiliation Institute of Human Genetics, Christian-Albrechts-University Kiel & University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Bernhard Horsthemke ,

* E-mail: bernhard.horsthemke@uni-due.de

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯
Karin Buiting

Affiliation Institut für Humangenetik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany
⨯

Deep Bisulfite Sequencing of Aberrantly Methylated Loci in a Patient with Multiple Methylation Defects

Jasmin Beygo,
Ole Ammerpohl,
Daniela Gritzan,
Melanie Heitmann,
Katrin Rademacher,
Julia Richter,
Almuth Caliebe,
Reiner Siebert,
Bernhard Horsthemke,
Karin Buiting

Published: October 9, 2013
https://doi.org/10.1371/journal.pone.0076953

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Blood
Is the Subject Area "Blood" applicable to this article?

Thanks for your feedback.
Genomic imprinting
Is the Subject Area "Genomic imprinting" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.
Methylation
Is the Subject Area "Methylation" applicable to this article?

Thanks for your feedback.
Heterozygosity
Is the Subject Area "Heterozygosity" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.