Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation

• Kuo-Feng Hua ,

  * E-mail: kfhua@niu.edu.tw

  Affiliation Department of Biotechnology and Animal Science, National Ilan University, Ilan, Taiwan

  ⨯
• Ju-Ching Chou,

  Affiliation Department of Biotechnology and Animal Science, National Ilan University, Ilan, Taiwan

  ⨯
• Yulin Lam,

  Affiliation Department of Chemistry, National University of Singapore, Singapore, Singapore

  ⨯
• Yu-Ling Tasi,

  Affiliation Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan

  ⨯
• Ann Chen,

  Affiliation Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

  ⨯
• Shuk-Man Ka,

  Affiliation Graduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan

  ⨯
• Zhanxiong Fang,

  Affiliation Department of Chemistry, National University of Singapore, Singapore, Singapore

  ⨯
• May-Lan Liu,

  Affiliation Department of Nutritional Science, Toko University, Chiayi, Taiwan

  ⨯
• Feng-Ling Yang,

  Affiliation Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

  ⨯
• Yu-Liang Yang,

  Affiliation Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan

  ⨯
• Yi-Chich Chiu,

  Affiliation Department of Biomechatronic Engineering, National Ilan University, Ilan, Taiwan

  ⨯
• Shih-Hsiung Wu

  Affiliation Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

  ⨯