Four Amino Acids within a Tandem QxVx Repeat in a Predicted Extended α-Helix of the Smad-Binding Domain of Sip1 Are Necessary for Binding to Activated Smad Proteins

Andrea Conidi; Veronique van den Berghe; Kris Leslie; Agata Stryjewska; Hua Xue; Ye-Guang Chen; Eve Seuntjens; Danny Huylebroeck

doi:10.1371/journal.pone.0076733

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Peer-reviewed

Research Article

Four Amino Acids within a Tandem QxVx Repeat in a Predicted Extended α-Helix of the Smad-Binding Domain of Sip1 Are Necessary for Binding to Activated Smad Proteins

Andrea Conidi,

Affiliations Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium, Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Veronique van den Berghe,

Affiliation Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium
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Kris Leslie,

Affiliation Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands
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Agata Stryjewska,

Affiliation Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium
⨯
Hua Xue,

Affiliation The State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua-Beijing Centre for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Ye-Guang Chen,

Affiliation The State Key Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua-Beijing Centre for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Eve Seuntjens,

Affiliation Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium
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Danny Huylebroeck

* E-mail: danny.huylebroeck@med.kuleuven.be

Affiliations Laboratory of Molecular Biology (Celgen), Department of Development and Regeneration, Katholieke Universiteit Leuven, Leuven, Belgium, Department of Cell Biology, Erasmus University Medical Center, Rotterdam, The Netherlands
⨯

Four Amino Acids within a Tandem QxVx Repeat in a Predicted Extended α-Helix of the Smad-Binding Domain of Sip1 Are Necessary for Binding to Activated Smad Proteins

Andrea Conidi,
Veronique van den Berghe,
Kris Leslie,
Agata Stryjewska,
Hua Xue,
Ye-Guang Chen,
Eve Seuntjens,
Danny Huylebroeck

Published: October 11, 2013
https://doi.org/10.1371/journal.pone.0076733

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