A Novel Cationic Microbubble Coated with Stearic Acid-Modified Polyethylenimine to Enhance DNA Loading and Gene Delivery by Ultrasound

Qiaofeng Jin; Zhiyong Wang; Fei Yan; Zhiting Deng; Fei Ni; Junru Wu; Robin Shandas; Xin Liu; Hairong Zheng

doi:10.1371/journal.pone.0076544

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Open Access

Peer-reviewed

Research Article

A Novel Cationic Microbubble Coated with Stearic Acid-Modified Polyethylenimine to Enhance DNA Loading and Gene Delivery by Ultrasound

Qiaofeng Jin,

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Zhiyong Wang,

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Fei Yan ,

* E-mail: hr.zheng@siat.ac.cn (HZ); fei.yan@siat.ac.cn (FY)

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Zhiting Deng,

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Fei Ni,

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Junru Wu,

Affiliation Department of Physics, University of Vermont, Burlington, Vermont, United States of America
⨯
Robin Shandas,

Affiliation Department of Bioengineering, University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, United States of America
⨯
Xin Liu,

Affiliations Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, Shenzhen Key Lab for MRI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯
Hairong Zheng

* E-mail: hr.zheng@siat.ac.cn (HZ); fei.yan@siat.ac.cn (FY)

Affiliation Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China
⨯

A Novel Cationic Microbubble Coated with Stearic Acid-Modified Polyethylenimine to Enhance DNA Loading and Gene Delivery by Ultrasound

Qiaofeng Jin,
Zhiyong Wang,
Fei Yan,
Zhiting Deng,
Fei Ni,
Junru Wu,
Robin Shandas,
Xin Liu,
Hairong Zheng

Published: September 26, 2013
https://doi.org/10.1371/journal.pone.0076544

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