Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells

• Enza Lonardo ,

  Contributed equally to this work with: Enza Lonardo, Michele Cioffi

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Michele Cioffi ,

  Contributed equally to this work with: Enza Lonardo, Michele Cioffi

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Patricia Sancho,

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Yolanda Sanchez-Ripoll,

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Sara Maria Trabulo,

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Jorge Dorado,

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Anamaria Balic,

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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• Manuel Hidalgo,

  Affiliation Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme (CNIO), Spanish National Cancer Research Centre, Madrid, Spain

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• Christopher Heeschen

  * E-mail: cheeschen@cnio.es

  Affiliation Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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