IGF-IR Promotes Prostate Cancer Growth by Stabilizing α5β1 Integrin Protein Levels

Open Access

Peer-reviewed

Research Article

IGF-IR Promotes Prostate Cancer Growth by Stabilizing α₅β₁ Integrin Protein Levels

Aejaz Sayeed,

Affiliation Department of Cancer Biology, Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Carmine Fedele,

Affiliation Department of Cancer Biology, Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
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Marco Trerotola,

Current address: Ce.S.I. – University of Chieti-Pescara, via colle dell'Ara, Chieti Scalo, Italy

Affiliation Department of Cancer Biology, Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Kirat K. Ganguly,

Affiliation Department of Cancer Biology, Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯
Lucia R. Languino

* E-mail: lucia.languino@jefferson.edu

Affiliation Department of Cancer Biology, Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America
⨯

Integrins
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Transfection
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Small interfering RNA
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Immunoblotting
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Prostate cancer
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Growth factors
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Cell proliferation
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Immunoprecipitation
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