Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

Filipa P. Reis; Ana Barbas; A. A. Klauer-King; Borislava Tsanova; Daneen Schaeffer; Eduardo López-Viñas; Paulino Gómez-Puertas; Ambro van Hoof; Cecília M. Arraiano

doi:10.1371/journal.pone.0076504

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Open Access

Peer-reviewed

Research Article

Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

Filipa P. Reis,

Affiliation Instituto de Tecnologia Química e Biológica - ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
Ana Barbas,

Current address: Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal

Affiliation Instituto de Tecnologia Química e Biológica - ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
A. A. Klauer-King,

Affiliation Department of Microbiology and Molecular Genetics, and The University of Texas Graduate School of Biomedical Sciences, University of Texas Health Science Center-Houston, Houston, Texas, United States of America
⨯
Borislava Tsanova,

Affiliation Department of Microbiology and Molecular Genetics, and The University of Texas Graduate School of Biomedical Sciences, University of Texas Health Science Center-Houston, Houston, Texas, United States of America
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Daneen Schaeffer,

Current address: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

Affiliation Department of Microbiology and Molecular Genetics, and The University of Texas Graduate School of Biomedical Sciences, University of Texas Health Science Center-Houston, Houston, Texas, United States of America
⨯
Eduardo López-Viñas,

Affiliations Centro de Biologia Molecular “Severo Ochoa” (CSIC-UAM), Campus Universidad Autonoma de Madrid, Madrid, Spain, Biomol-Informatics SL, Madrid, Spain
⨯
Paulino Gómez-Puertas,

Affiliation Centro de Biologia Molecular “Severo Ochoa” (CSIC-UAM), Campus Universidad Autonoma de Madrid, Madrid, Spain
⨯
Ambro van Hoof,

Affiliation Department of Microbiology and Molecular Genetics, and The University of Texas Graduate School of Biomedical Sciences, University of Texas Health Science Center-Houston, Houston, Texas, United States of America
⨯
Cecília M. Arraiano

* E-mail: cecilia@itqb.unl.pt

Affiliation Instituto de Tecnologia Química e Biológica - ITQB, Universidade Nova de Lisboa, Oeiras, Portugal
⨯

Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

Filipa P. Reis,
Ana Barbas,
A. A. Klauer-King,
Borislava Tsanova,
Daneen Schaeffer,
Eduardo López-Viñas,
Paulino Gómez-Puertas,
Ambro van Hoof,
Cecília M. Arraiano

Published: November 12, 2013
https://doi.org/10.1371/journal.pone.0076504

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Ribonucleases
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Exosomes
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Nucleotides
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RNA structure
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