Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer’s Disease

Alice Krezymon; Kevin Richetin; Hélène Halley; Laurent Roybon; Jean-Michel Lassalle; Bernard Francès; Laure Verret; Claire Rampon

doi:10.1371/journal.pone.0076497

Loading metrics

Open Access

Peer-reviewed

Research Article

Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer’s Disease

Alice Krezymon,

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Kevin Richetin,

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Hélène Halley,

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Laurent Roybon,

Affiliation Multi Park, Department of Experimental Medical Science, Wallenberg Neuroscience Center, Lund University, Lund, Sweden
⨯
Jean-Michel Lassalle,

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Bernard Francès,

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Laure Verret ,

Contributed equally to this work with: Laure Verret, Claire Rampon

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯
Claire Rampon

Contributed equally to this work with: Laure Verret, Claire Rampon

* E-mail: claire.rampon@univ-tlse3.fr

Affiliations Université de Toulouse (UPS) Centre de Recherches sur la Cognition Animale, Toulouse, France, Centre National de la Recherche Scientifique (CNRS) Centre de Recherches sur la Cognition Animale, Toulouse, France
⨯

Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer’s Disease

Alice Krezymon,
Kevin Richetin,
Hélène Halley,
Laurent Roybon,
Jean-Michel Lassalle,
Bernard Francès,
Laure Verret,
Claire Rampon

Published: September 27, 2013
https://doi.org/10.1371/journal.pone.0076497

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Neuronal dendrites
Is the Subject Area "Neuronal dendrites" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Dentate gyrus
Is the Subject Area "Dentate gyrus" applicable to this article?

Thanks for your feedback.
Hippocampal neurogenesis
Is the Subject Area "Hippocampal neurogenesis" applicable to this article?

Thanks for your feedback.
Alzheimer's disease
Is the Subject Area "Alzheimer's disease" applicable to this article?

Thanks for your feedback.
Neuronal morphology
Is the Subject Area "Neuronal morphology" applicable to this article?

Thanks for your feedback.