Peptide-Derivatized SB105-A10 Dendrimer Inhibits the Infectivity of R5 and X4 HIV-1 Strains in Primary PBMCs and Cervicovaginal Histocultures

Isabella Bon; David Lembo; Marco Rusnati; Alberto Clò; Silvia Morini; Anna Miserocchi; Antonella Bugatti; Sonia Grigolon; Giuseppina Musumeci; Santo Landolfo; Maria Carla Re; Davide Gibellini

doi:10.1371/journal.pone.0076482

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Open Access

Peer-reviewed

Research Article

Peptide-Derivatized SB105-A10 Dendrimer Inhibits the Infectivity of R5 and X4 HIV-1 Strains in Primary PBMCs and Cervicovaginal Histocultures

Isabella Bon,

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯
David Lembo,

Affiliation Department of Clinical and Biological Sciences, University of Torino, Orbassano, Torino, Italy
⨯
Marco Rusnati,

Affiliation Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy
⨯
Alberto Clò,

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯
Silvia Morini,

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯
Anna Miserocchi,

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯
Antonella Bugatti,

Affiliation Department of Biomedical Sciences and Biotechnology, University of Brescia, Brescia, Italy
⨯
Sonia Grigolon,

Affiliation Spider Biotech srl, Colleretto Giacosa, Torino, Italy
⨯
Giuseppina Musumeci,

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯
Santo Landolfo,

Affiliation Department of Public Health and Microbiology, University of Torino, Torino, Italy
⨯
Maria Carla Re,

Affiliations Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy, Interuniversity Consortium, National Institute Biostructure and Biosystems (INBB) Roma, Italy
⨯
Davide Gibellini

* E-mail: davide.gibellini@unibo.it

Affiliation Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Microbiology Section, University of Bologna, Bologna, Italy
⨯

Peptide-Derivatized SB105-A10 Dendrimer Inhibits the Infectivity of R5 and X4 HIV-1 Strains in Primary PBMCs and Cervicovaginal Histocultures

Isabella Bon,
David Lembo,
Marco Rusnati,
Alberto Clò,
Silvia Morini,
Anna Miserocchi,
Antonella Bugatti,
Sonia Grigolon,
Giuseppina Musumeci,
Santo Landolfo

Published: October 7, 2013
https://doi.org/10.1371/journal.pone.0076482

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