A Polymorphic 3’UTR Element in ATP1B1 Regulates Alternative Polyadenylation and Is Associated with Blood Pressure

Megana K. Prasad; Kavita Bhalla; Zhen Hua Pan; Jeffrey R. O’Connell; Alan B. Weder; Aravinda Chakravarti; Bin Tian; Yen-Pei C. Chang

doi:10.1371/journal.pone.0076290

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Peer-reviewed

Research Article

A Polymorphic 3’UTR Element in ATP1B1 Regulates Alternative Polyadenylation and Is Associated with Blood Pressure

Megana K. Prasad ,

Contributed equally to this work with: Megana K. Prasad, Kavita Bhalla

Affiliation Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Kavita Bhalla ,

Contributed equally to this work with: Megana K. Prasad, Kavita Bhalla

Affiliation Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Zhen Hua Pan,

Affiliation Department of Biochemistry & Molecular Biology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, United States of America
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Jeffrey R. O’Connell,

Affiliation Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Alan B. Weder,

Affiliation Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America
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Aravinda Chakravarti,

Affiliation McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Bin Tian,

Affiliation Department of Biochemistry & Molecular Biology, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, United States of America
⨯
Yen-Pei C. Chang

* E-mail: cchang@medicine.umaryland.edu

Affiliation Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯

A Polymorphic 3’UTR Element in ATP1B1 Regulates Alternative Polyadenylation and Is Associated with Blood Pressure

Megana K. Prasad,
Kavita Bhalla,
Zhen Hua Pan,
Jeffrey R. O’Connell,
Alan B. Weder,
Aravinda Chakravarti,
Bin Tian,
Yen-Pei C. Chang

Published: October 1, 2013
https://doi.org/10.1371/journal.pone.0076290

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Polyadenylation
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Messenger RNA
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Kidneys
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3' UTR
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Adenosine triphosphatase
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Lymphocytes
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Single nucleotide polymorphisms
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Blood pressure
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