The Jagged-2/Notch-1/Hes-1 Pathway Is Involved in Intestinal Epithelium Regeneration after Intestinal Ischemia-Reperfusion Injury

Guoqing Chen; Yuan Qiu; Lihua Sun; Min Yu; Wensheng Wang; Weidong Xiao; Yang Yang; Yong Liu; Songwei Yang; Daniel H. Teitelbaum; Yuanhang Ma; Dingsong Lu; Hua Yang

doi:10.1371/journal.pone.0076274

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Open Access

Peer-reviewed

Research Article

The Jagged-2/Notch-1/Hes-1 Pathway Is Involved in Intestinal Epithelium Regeneration after Intestinal Ischemia-Reperfusion Injury

Guoqing Chen ,

Contributed equally to this work with: Guoqing Chen, Yuan Qiu

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Yuan Qiu ,

Contributed equally to this work with: Guoqing Chen, Yuan Qiu

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Lihua Sun,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Min Yu,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Wensheng Wang,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Weidong Xiao,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Yang Yang,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Yong Liu,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Songwei Yang,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Daniel H. Teitelbaum,

Affiliation Department of Surgery, the University of Michigan Medical School, Ann Arbor, Michigan
⨯
Yuanhang Ma,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Dingsong Lu,

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯
Hua Yang

* E-mail: huayang@tmmu.edu.cn

Affiliation Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China
⨯

The Jagged-2/Notch-1/Hes-1 Pathway Is Involved in Intestinal Epithelium Regeneration after Intestinal Ischemia-Reperfusion Injury

Guoqing Chen,
Yuan Qiu,
Lihua Sun,
Min Yu,
Wensheng Wang,
Weidong Xiao,
Yang Yang,
Yong Liu,
Songwei Yang,
Daniel H. Teitelbaum

Published: October 3, 2013
https://doi.org/10.1371/journal.pone.0076274

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Gastrointestinal tract
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Notch signaling
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Small interfering RNA
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Epithelial cells
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Protein expression
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Epithelium
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