Subcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-Sequence Retaining Transcripts in Mouse and Rat Neurons

Mugdha Khaladkar; Peter T. Buckley; Miler T. Lee; Chantal Francis; Mitra M. Eghbal; Tina Chuong; Sangita Suresh; Bernhard Kuhn; James Eberwine; Junhyong Kim

doi:10.1371/journal.pone.0076194

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Peer-reviewed

Research Article

Subcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-Sequence Retaining Transcripts in Mouse and Rat Neurons

Mugdha Khaladkar,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Peter T. Buckley,

Affiliations Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Miler T. Lee,

Affiliation Department of Genetics, Yale University, New Haven, Connecticut, United States of America
⨯
Chantal Francis,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Mitra M. Eghbal,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Tina Chuong,

Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Sangita Suresh,

Affiliation Department of Pediatrics, Boston Children’s Hospital, Boston, Massachusetts, United States of America
⨯
Bernhard Kuhn,

Affiliation Department of Pediatrics, Boston Children’s Hospital, Boston, Massachusetts, United States of America
⨯
James Eberwine ,

* E-mail: junhyong@sas.upenn.edu (JK); eberwine@mail.med.upenn.edu (JE)

Affiliations Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Junhyong Kim

* E-mail: junhyong@sas.upenn.edu (JK); eberwine@mail.med.upenn.edu (JE)

Affiliations Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Penn Genome Frontiers Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Genomics and Computational Biology Program, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Subcellular RNA Sequencing Reveals Broad Presence of Cytoplasmic Intron-Sequence Retaining Transcripts in Mouse and Rat Neurons

Mugdha Khaladkar,
Peter T. Buckley,
Miler T. Lee,
Chantal Francis,
Mitra M. Eghbal,
Tina Chuong,
Sangita Suresh,
Bernhard Kuhn,
James Eberwine,
Junhyong Kim

Published: October 3, 2013
https://doi.org/10.1371/journal.pone.0076194

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Introns
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Neuronal dendrites
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RNA sequencing
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Hippocampus
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Cardiomyocytes
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Non-coding RNA
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Messenger RNA
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Brown adipose tissue
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