The Origin of Biased Sequence Depth in Sequence-Independent Nucleic Acid Amplification and Optimization for Efficient Massive Parallel Sequencing

• Toon Rosseel ,

  Contributed equally to this work with: Toon Rosseel, Steven Van Borm

  Affiliation Operational Directorate of Virology, Veterinary and Agrochemical Research Centre, Ukkel, Brussels, Belgium

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• Steven Van Borm ,

  Contributed equally to this work with: Toon Rosseel, Steven Van Borm

  * E-mail: stevenvanborm@coda-cerva.be

  Affiliation Operational Directorate of Virology, Veterinary and Agrochemical Research Centre, Ukkel, Brussels, Belgium

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• Frank Vandenbussche,

  Affiliation Operational Directorate of Virology, Veterinary and Agrochemical Research Centre, Ukkel, Brussels, Belgium

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• Bernd Hoffmann,

  Affiliation Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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• Thierry van den Berg,

  Affiliation Operational Directorate of Virology, Veterinary and Agrochemical Research Centre, Ukkel, Brussels, Belgium

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• Martin Beer,

  Affiliation Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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• Dirk Höper

  Affiliation Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany

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