A Strategy for Synthesis of Pathogenic Human Immunoglobulin Free Light Chains in E. coli

Paola Rognoni; Francesca Lavatelli; Simona Casarini; Giovanni Palladini; Laura Verga; Paolo Pedrazzoli; Giovanna Valentini; Giampaolo Merlini; Vittorio Perfetti

doi:10.1371/journal.pone.0076022

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Peer-reviewed

Research Article

A Strategy for Synthesis of Pathogenic Human Immunoglobulin Free Light Chains in E. coli

Paola Rognoni,

Affiliation Amyloidosis Research and Treatment Center and Biotechnology Research Laboratories, Fondazione IRCCS Policlinico S. Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy
⨯
Francesca Lavatelli,

Affiliation Amyloidosis Research and Treatment Center and Biotechnology Research Laboratories, Fondazione IRCCS Policlinico S. Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy
⨯
Simona Casarini,

Affiliation Amyloidosis Research and Treatment Center and Biotechnology Research Laboratories, Fondazione IRCCS Policlinico S. Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy
⨯
Giovanni Palladini,

Affiliation Amyloidosis Research and Treatment Center and Biotechnology Research Laboratories, Fondazione IRCCS Policlinico S. Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy
⨯
Laura Verga,

Affiliation Pathologic Unit, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy
⨯
Paolo Pedrazzoli,

Affiliation Department of Hematology and Oncology, Section of Oncology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy
⨯
Giovanna Valentini,

Affiliation Department of Biology and Biotechnology “Lazzaro Spallanzani”, University of Pavia, Pavia, Italy
⨯
Giampaolo Merlini,

Affiliation Amyloidosis Research and Treatment Center and Biotechnology Research Laboratories, Fondazione IRCCS Policlinico S. Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy
⨯
Vittorio Perfetti

* E-mail: v.perfetti@smatteo.pv.it

Affiliation Department of Hematology and Oncology, Section of Oncology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy
⨯

A Strategy for Synthesis of Pathogenic Human Immunoglobulin Free Light Chains in E. coli

Paola Rognoni,
Francesca Lavatelli,
Simona Casarini,
Giovanni Palladini,
Laura Verga,
Paolo Pedrazzoli,
Giovanna Valentini,
Giampaolo Merlini,
Vittorio Perfetti

Published: September 27, 2013
https://doi.org/10.1371/journal.pone.0076022

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