Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice

Gang Cheng; Arun P. Palanisamy; Zachary P. Evans; Alton G. Sutter; Lan Jin; Inderjit Singh; Harold May; Michael G. Schmidt; Kenneth D. Chavin

doi:10.1371/journal.pone.0075980

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Peer-reviewed

Research Article

Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice

Gang Cheng ,

Contributed equally to this work with: Gang Cheng, Arun P. Palanisamy

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Arun P. Palanisamy ,

Contributed equally to this work with: Gang Cheng, Arun P. Palanisamy

* E-mail: arunp@musc.edu

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Zachary P. Evans,

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Alton G. Sutter,

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Lan Jin,

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Inderjit Singh,

Affiliation Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Harold May,

Affiliation Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Michael G. Schmidt,

Affiliation Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Kenneth D. Chavin

Affiliation Divisions of Transplant Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯

Cerulenin Blockade of Fatty Acid Synthase Reverses Hepatic Steatosis in ob/ob Mice

Gang Cheng,
Arun P. Palanisamy,
Zachary P. Evans,
Alton G. Sutter,
Lan Jin,
Inderjit Singh,
Harold May,
Michael G. Schmidt,
Kenneth D. Chavin

Published: September 27, 2013
https://doi.org/10.1371/journal.pone.0075980

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