Systemic Delivery of shRNA by AAV9 Provides Highly Efficient Knockdown of Ubiquitously Expressed GFP in Mouse Heart, but Not Liver

Open Access

Peer-reviewed

Research Article

Bryan A. Piras,

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America
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Daniel M. O’Connor,

Current address: Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Brent A. French

* E-mail: bf4g@eservices.virginia.edu

Affiliations Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America, Department of Radiology, University of Virginia, Charlottesville, Virginia, United States of America, Department of Medicine/Cardiovascular Medicine, University of Virginia, Charlottesville, Virginia, United States of America
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Heart
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Green fluorescent protein
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Viral genome
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Mammalian genomics
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Messenger RNA
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Luciferase
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Cardiomyocytes
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Plasmid construction
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