Pipoxolan Ameliorates Cerebral Ischemia via Inhibition of Neuronal Apoptosis and Intimal Hyperplasia through Attenuation of VSMC Migration and Modulation of Matrix Metalloproteinase-2/9 and Ras/MEK/ERK Signaling Pathways

• Yuh-Fung Chen ,

  * E-mail: yfchen@mail.cmu.edu.tw

  Affiliations Department of Pharmacology, College of Medicine, China Medical University, Taichung, Taiwan, Department of Pharmacy, China Medical University Hospital, Taichung, Taiwan

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• Huei-Yann Tsai,

  Affiliation Department of Pharmacy, China Medical University Hospital, Taichung, Taiwan

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• Kuo-Jen Wu,

  Affiliation Department of Pharmacology, College of Medicine, China Medical University, Taichung, Taiwan

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• Lian-Ru Siao,

  Affiliation Department of Pharmacology, College of Medicine, China Medical University, Taichung, Taiwan

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• W. Gibson Wood

  Affiliation Department of Pharmacology, University of Minnesota and Geriatric Research, Education and Clinical Center, VA Medical Center, Minneapolis, Minnesota, United States of America

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