SULF2 Methylation Is Associated with In Vitro Cisplatin Sensitivity and Clinical Efficacy for Gastric Cancer Patients Treated with a Modified FOLFOX Regimen

Jie Shen; Jia Wei; Hao Wang; Yang Yang; Guofeng Yue; Lin Wang; Lixia Yu; Li Xie; Xia Sun; Xinyu Bian; Zhengyun Zou; Xiaoping Qian; Wenxian Guan; Baorui Liu

doi:10.1371/journal.pone.0075564

Loading metrics

Open Access

Peer-reviewed

Research Article

SULF2 Methylation Is Associated with In Vitro Cisplatin Sensitivity and Clinical Efficacy for Gastric Cancer Patients Treated with a Modified FOLFOX Regimen

Jie Shen,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Jia Wei,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Hao Wang,

Affiliation Department of General Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China
⨯
Yang Yang,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Guofeng Yue,

Affiliation Nanjing Medical University, Nanjing, Jiangsu, China
⨯
Lin Wang,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Lixia Yu,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Li Xie,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Xia Sun,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Xinyu Bian,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Zhengyun Zou,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Xiaoping Qian,

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯
Wenxian Guan ,

* E-mail: guanwenxiannj@163.com (WG); baoruiliu@nju.edu.cn (BL)

Affiliation Department of General Surgery, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China
⨯
Baorui Liu

* E-mail: guanwenxiannj@163.com (WG); baoruiliu@nju.edu.cn (BL)

Affiliation The Comprehensive Cancer Centre, Drum Tower Hospital, Medical School of Nanjing University, Clinical Cancer Institute of Nanjing University, Nanjing, Jiangsu, China
⨯

SULF2 Methylation Is Associated with In Vitro Cisplatin Sensitivity and Clinical Efficacy for Gastric Cancer Patients Treated with a Modified FOLFOX Regimen

Jie Shen,
Jia Wei,
Hao Wang,
Yang Yang,
Guofeng Yue,
Lin Wang,
Lixia Yu,
Li Xie,
Xia Sun,
Xinyu Bian

Published: October 4, 2013
https://doi.org/10.1371/journal.pone.0075564

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gastric cancer
Is the Subject Area "Gastric cancer" applicable to this article?

Thanks for your feedback.
DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Methylation
Is the Subject Area "Methylation" applicable to this article?

Thanks for your feedback.
Non-small cell lung cancer
Is the Subject Area "Non-small cell lung cancer" applicable to this article?

Thanks for your feedback.
Histology
Is the Subject Area "Histology" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.