Bofu-Tsu-Shosan, an Oriental Herbal Medicine, Exerts a Combinatorial Favorable Metabolic Modulation Including Antihypertensive Effect on a Mouse Model of Human Metabolic Disorders with Visceral Obesity

Kengo Azushima; Kouichi Tamura; Hiromichi Wakui; Akinobu Maeda; Masato Ohsawa; Kazushi Uneda; Ryu Kobayashi; Tomohiko Kanaoka; Toru Dejima; Tetsuya Fujikawa; Akio Yamashita; Yoshiyuki Toya; Satoshi Umemura

doi:10.1371/journal.pone.0075560

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Research Article

Bofu-Tsu-Shosan, an Oriental Herbal Medicine, Exerts a Combinatorial Favorable Metabolic Modulation Including Antihypertensive Effect on a Mouse Model of Human Metabolic Disorders with Visceral Obesity

Kengo Azushima,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Kouichi Tamura ,

* E-mail: tamukou@med.yokohama-cu.ac.jp

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Hiromichi Wakui,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Akinobu Maeda,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Masato Ohsawa,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Kazushi Uneda,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Ryu Kobayashi,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Tomohiko Kanaoka,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Toru Dejima,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Tetsuya Fujikawa,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Akio Yamashita,

Affiliation Department of Molecular Biology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Yoshiyuki Toya,

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯
Satoshi Umemura

Affiliation Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan
⨯

Bofu-Tsu-Shosan, an Oriental Herbal Medicine, Exerts a Combinatorial Favorable Metabolic Modulation Including Antihypertensive Effect on a Mouse Model of Human Metabolic Disorders with Visceral Obesity

Kengo Azushima,
Kouichi Tamura,
Hiromichi Wakui,
Akinobu Maeda,
Masato Ohsawa,
Kazushi Uneda,
Ryu Kobayashi,
Tomohiko Kanaoka,
Toru Dejima,
Tetsuya Fujikawa

Published: October 9, 2013
https://doi.org/10.1371/journal.pone.0075560

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