Spinal Actions of Lipoxin A4 and 17(R)-Resolvin D1 Attenuate Inflammation-Induced Mechanical Hypersensitivity and Spinal TNF Release

Open Access

Peer-reviewed

Research Article

Spinal Actions of Lipoxin A₄ and 17(R)-Resolvin D1 Attenuate Inflammation-Induced Mechanical Hypersensitivity and Spinal TNF Release

Sally Abdelmoaty,

Affiliations Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
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Gustaf Wigerblad,

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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Duygu B. Bas,

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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Simone Codeluppi,

Affiliation Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
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Teresa Fernandez-Zafra,

Affiliation Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden
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El-Sayed El-Awady,

Affiliation Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
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Yasser Moustafa,

Affiliation Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt
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Alaa El-din S. Abdelhamid,

Affiliation Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt
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Ernst Brodin,

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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Camilla I. Svensson

* E-mail: camilla.svensson@ki.se

Affiliation Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
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Astrocytes
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Inflammation
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Spinal cord
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Cytokines
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Hypersensitivity
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Pain
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Cell cultures
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Microglial cells
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