Engineering Salidroside Biosynthetic Pathway in Hairy Root Cultures of Rhodiola crenulata Based on Metabolic Characterization of Tyrosine Decarboxylase

Xiaozhong Lan; Kai Chang; Lingjiang Zeng; Xiaoqiang Liu; Fei Qiu; Weilie Zheng; Hong Quan; Zhihua Liao; Min Chen; Wenlin Huang; Wanhong Liu; Qiang Wang

doi:10.1371/journal.pone.0075459

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Open Access

Peer-reviewed

Research Article

Engineering Salidroside Biosynthetic Pathway in Hairy Root Cultures of Rhodiola crenulata Based on Metabolic Characterization of Tyrosine Decarboxylase

Xiaozhong Lan ,

Contributed equally to this work with: Xiaozhong Lan, Kai Chang

Affiliations Agricultural and Animal Husbandry College, Tibet University, Nyingchi of Tibet, P. R. China, Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Kai Chang ,

Contributed equally to this work with: Xiaozhong Lan, Kai Chang

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Lingjiang Zeng,

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Xiaoqiang Liu,

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Fei Qiu,

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Weilie Zheng,

Affiliation Agricultural and Animal Husbandry College, Tibet University, Nyingchi of Tibet, P. R. China
⨯
Hong Quan,

Affiliation Agricultural and Animal Husbandry College, Tibet University, Nyingchi of Tibet, P. R. China
⨯
Zhihua Liao ,

* E-mail: zhliao@swu.edu.cn (ZHL); mminchen@163.com (MC)

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Min Chen ,

* E-mail: zhliao@swu.edu.cn (ZHL); mminchen@163.com (MC)

Affiliation School of Pharmaceutical Sciences, Southwest University, Chongqing, P. R. China
⨯
Wenlin Huang,

Affiliation Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), Chongqing Engineering and Technology Research Center for Sweetpotato, School of Life Sciences, Southwest University, Chongqing, P. R. China
⨯
Wanhong Liu,

Affiliation School of Chemistry and Chemical Engineering, Chongqing University of Science and Technology, Chongqing, P. R. China
⨯
Qiang Wang

Affiliation China Rural Technology Development Center, Ministry of Science and Technology, Beijing, P. R. China
⨯

Engineering Salidroside Biosynthetic Pathway in Hairy Root Cultures of Rhodiola crenulata Based on Metabolic Characterization of Tyrosine Decarboxylase

Xiaozhong Lan,
Kai Chang,
Lingjiang Zeng,
Xiaoqiang Liu,
Fei Qiu,
Weilie Zheng,
Hong Quan,
Zhihua Liao,
Min Chen,
Wenlin Huang

Published: October 4, 2013
https://doi.org/10.1371/journal.pone.0075459

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Tyrosine
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Gene expression
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