Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

Elke Gülden; Masaru Ihira; Atsushi Ohashi; Anna Lena Reinbeck; Marina A. Freudenberg; Hubert Kolb; Volker Burkart

doi:10.1371/journal.pone.0075385

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Research Article

Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

Elke Gülden,

Current address: Yale University School of Medicine, New Haven, Connecticut, United States of America

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯
Masaru Ihira,

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯
Atsushi Ohashi,

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯
Anna Lena Reinbeck,

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯
Marina A. Freudenberg,

Affiliation Department of Developmental Immunology, Max-Planck-Institute of Immunbiology and Epigenetics, Freiburg, Germany
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Hubert Kolb,

Current address: West German Centre of Diabetes and Health, Verbund Katholischer Kliniken Düsseldorf, Düsseldorf, Germany

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯
Volker Burkart

* E-mail: burkart@ddz.uni-duesseldorf.de

Affiliation Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research, Member of the German Center for Diabetes Research (DZD), Düsseldorf, Germany
⨯

Toll-Like Receptor 4 Deficiency Accelerates the Development of Insulin-Deficient Diabetes in Non-Obese Diabetic Mice

Elke Gülden,
Masaru Ihira,
Atsushi Ohashi,
Anna Lena Reinbeck,
Marina A. Freudenberg,
Hubert Kolb,
Volker Burkart

Published: September 23, 2013
https://doi.org/10.1371/journal.pone.0075385

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Toll-like receptors
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