Specific Increase in MDR1 Mediated Drug-Efflux in Human Brain Endothelial Cells following Co-Exposure to HIV-1 and Saquinavir

Open Access

Peer-reviewed

Research Article

Upal Roy ,

* E-mail: uroy@fiu.edu

Current address: Department of Immunology, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, United States of America

Affiliation Department of Pharmacology, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Christine Bulot,

Affiliation Department of Pharmacology, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Kerstin Honer zu Bentrup,

Affiliation Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯
Debasis Mondal

Affiliation Department of Pharmacology, Tulane University Health Sciences Center, New Orleans, Louisiana, United States of America
⨯

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HIV-1
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Small interfering RNA
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Gene expression
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Central nervous system
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Transfection
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Highly-active antiretroviral therapy
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Inflammation
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Endothelial cells
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