Enhanced Production of Recombinant Secretory Proteins in Pichia pastoris by Optimizing Kex2 P1’ site

• Song Yang,

  Affiliation Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

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• Ye Kuang,

  Affiliations Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, Department of Biomedical Engineering, School of Pharmaceutical Sciences, Jilin University, Changchun, China

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• Hongbo Li,

  Affiliations Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, Key Laboratory of Research and Utilization of Ethnomedicinal Plant Resources of Hunan Province, Department of Life Sciences, Huaihua College, Huaihua, China

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• Yuehong Liu,

  Affiliations Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, Department of Biomedical Engineering, School of Pharmaceutical Sciences, Jilin University, Changchun, China

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• Xiaoyan Hui,

  Affiliation Department of Medicine, The University of Hong Kong, Hong Kong, China

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• Peng Li,

  Affiliation Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

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• Zhiwu Jiang,

  Affiliation Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

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• Yulai Zhou,

  Affiliation Department of Biomedical Engineering, School of Pharmaceutical Sciences, Jilin University, Changchun, China

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• Yu Wang,

  Affiliations Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, Department of Medicine, The University of Hong Kong, Hong Kong, China

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• Aimin Xu,

  Affiliations Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China, Department of Medicine, The University of Hong Kong, Hong Kong, China

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• Shiwu Li,

  Affiliation Department of Pathology, University of Florida, Gainesville, Florida, United States of America

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• Pentao Liu,

  Affiliation Wellcome Trust Sanger Institute, Cambridge, United Kingdom

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• Donghai Wu

  * E-mail: dhwu2001@gmail.com

  Affiliation Key Laboratory of Regenerative Biology and The Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China

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