Dynamics of the Major Histocompatibility Complex Class I Processing and Presentation Pathway in the Course of Malaria Parasite Development in Human Hepatocytes: Implications for Vaccine Development

Jinxia Ma; Stefanie Trop; Samantha Baer; Elian Rakhmanaliev; Zita Arany; Peter Dumoulin; Hao Zhang; Julia Romano; Isabelle Coppens; Victor Levitsky; Jelena Levitskaya

doi:10.1371/journal.pone.0075321

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Open Access

Peer-reviewed

Research Article

Dynamics of the Major Histocompatibility Complex Class I Processing and Presentation Pathway in the Course of Malaria Parasite Development in Human Hepatocytes: Implications for Vaccine Development

Jinxia Ma,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Stefanie Trop,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Samantha Baer,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Elian Rakhmanaliev,

Current address: Vela Diagnostics Pte Ltd., Singapore, Singapore

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Zita Arany,

Current address: Roche Glycart AG, Schlieren, Switzerland

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Peter Dumoulin,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Hao Zhang,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Julia Romano,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Isabelle Coppens,

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Victor Levitsky,

Current address: Roche Glycart AG, Schlieren, Switzerland

Affiliation Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Jelena Levitskaya

* E-mail: jelevits@jhsph.edu

Affiliation W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯

Dynamics of the Major Histocompatibility Complex Class I Processing and Presentation Pathway in the Course of Malaria Parasite Development in Human Hepatocytes: Implications for Vaccine Development

Jinxia Ma,
Stefanie Trop,
Samantha Baer,
Elian Rakhmanaliev,
Zita Arany,
Peter Dumoulin,
Hao Zhang,
Julia Romano,
Isabelle Coppens,
Victor Levitsky

Published: September 25, 2013
https://doi.org/10.1371/journal.pone.0075321

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Major histocompatibility complex
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MHC class I genes
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Parasitic diseases
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Plasmodium
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Hepatocytes
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Malarial parasites
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Malaria
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Parasite replication
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