Protein Kinase CK2 Inhibition Down Modulates the NF-κB and STAT3 Survival Pathways, Enhances the Cellular Proteotoxic Stress and Synergistically Boosts the Cytotoxic Effect of Bortezomib on Multiple Myeloma and Mantle Cell Lymphoma Cells

• Sabrina Manni,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Alessandra Brancalion,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Elisa Mandato,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Laura Quotti Tubi,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Anna Colpo,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Marco Pizzi,

  Affiliation Department of Medicine, General Pathology and Cytopathology Unit, University of Padova, Padova, Italy

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• Rocco Cappellesso,

  Affiliation Department of Medicine, General Pathology and Cytopathology Unit, University of Padova, Padova, Italy

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• Fortunato Zaffino,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Speranza Antonia Di Maggio,

  Affiliation Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy

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• Anna Cabrelle,

  Affiliation Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Filippo Marino,

  Affiliation Department of Medicine, General Pathology and Cytopathology Unit, University of Padova, Padova, Italy

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• Renato Zambello,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Livio Trentin,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Fausto Adami,

  Affiliation Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy

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• Carmela Gurrieri,

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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• Gianpietro Semenzato ,

  * E-mail: francesco.piazza@unipd.it (FP); g.semenzato@unipd.it (GS)

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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•  [ ... ],
• Francesco Piazza

  * E-mail: francesco.piazza@unipd.it (FP); g.semenzato@unipd.it (GS)

  Affiliations Department of Medicine, Hematology and Clinical Immunology Branch, University of Padova, Padova, Italy, Myeloma and Lymphoma Pathobiology Laboratory, Hematologic Malignancies Unit, Venetian Institute of Molecular Medicine, Padova, Italy

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