The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences

Delphine Carbonnelle; Virginie Vignard; Delphine Sehedic; Agnes Moreau-Aubry; Laetitia Florenceau; Maud Charpentier; Wolfgang Mikulits; Nathalie Labarriere; François Lang

doi:10.1371/journal.pone.0075233

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Research Article

The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences

Delphine Carbonnelle,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
Virginie Vignard,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France, CHU Nantes, Nantes, France
⨯
Delphine Sehedic,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
Agnes Moreau-Aubry,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
Laetitia Florenceau,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
Maud Charpentier,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
Wolfgang Mikulits,

Affiliation Institute of Cancer Research, Comprehensive Cancer Center, Vienna, Austria
⨯
Nathalie Labarriere,

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯
François Lang

* E-mail: francois.lang@univ-nantes.fr

Affiliations Institut National de la Santé et de la Recherche Médicale, U892, Nantes, France, University of Nantes, Nantes, France, Centre national de la recherche scientifique, UMR 6299, Nantes, France
⨯

The Melanoma Antigens MELOE-1 and MELOE-2 Are Translated from a Bona Fide Polycistronic mRNA Containing Functional IRES Sequences

Delphine Carbonnelle,
Virginie Vignard,
Delphine Sehedic,
Agnes Moreau-Aubry,
Laetitia Florenceau,
Maud Charpentier,
Wolfgang Mikulits,
Nathalie Labarriere,
François Lang

Published: September 25, 2013
https://doi.org/10.1371/journal.pone.0075233

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Transfection
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Melanoma cells
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Small interfering RNA
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Messenger RNA
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Internal ribosome entry site
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T cells
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Melanoma
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Protein translation
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