Ansamitocin P3 Depolymerizes Microtubules and Induces Apoptosis by Binding to Tubulin at the Vinblastine Site

Open Access

Peer-reviewed

Research Article

Jubina B. Venghateri,

Affiliation IITB-Monash Research Academy, Indian Institute of Technology Bombay, Mumbai, India
⨯
Tilak Kumar Gupta,

Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, India
⨯
Paul J. Verma,

Affiliation Centre for Reproduction and Development, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia
⨯
Ambarish Kunwar,

Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, India
⨯
Dulal Panda

* E-mail: panda@iitb.ac.in

Affiliation Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai, India
⨯

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Tubulins
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Apoptosis
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Microtubules
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Binding analysis
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Cell staining
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Cysteine
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Hydrogen bonding
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Cell proliferation
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