Higher Serum Direct Bilirubin Levels Were Associated with a Lower Risk of Incident Chronic Kidney Disease in Middle Aged Korean Men

Seungho Ryu; Yoosoo Chang; Yiyi Zhang; Hee-Yeon Woo; Min-Jung Kwon; Hyosoon Park; Kyu-Beck Lee; Hee Jung Son; Juhee Cho; Eliseo Guallar

doi:10.1371/journal.pone.0075178

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Open Access

Peer-reviewed

Research Article

Higher Serum Direct Bilirubin Levels Were Associated with a Lower Risk of Incident Chronic Kidney Disease in Middle Aged Korean Men

Seungho Ryu,

Affiliations Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Yoosoo Chang,

Affiliations Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea, Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Yiyi Zhang,

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Hee-Yeon Woo,

Affiliation Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Min-Jung Kwon,

Affiliation Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Hyosoon Park,

Affiliation Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Kyu-Beck Lee,

Affiliation Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, South Korea
⨯
Hee Jung Son,

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Internal Medicine, Samsung Medical Center, Gangnam-Gu, Seoul, Korea
⨯
Juhee Cho,

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Samsung Comprehensive Cancer Center, Samsung Medical Center, Gangnam-Gu, Seoul, Seoul, Korea
⨯
Eliseo Guallar

* E-mail: eguallar@jhsph.edu

Affiliations Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America, Department of Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯

Higher Serum Direct Bilirubin Levels Were Associated with a Lower Risk of Incident Chronic Kidney Disease in Middle Aged Korean Men

Seungho Ryu,
Yoosoo Chang,
Yiyi Zhang,
Hee-Yeon Woo,
Min-Jung Kwon,
Hyosoon Park,
Kyu-Beck Lee,
Hee Jung Son,
Juhee Cho,
Eliseo Guallar

Published: February 20, 2014
https://doi.org/10.1371/journal.pone.0075178

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