Reducing FLI1 Levels in the MRL/lpr Lupus Mouse Model Impacts T Cell Function by Modulating Glycosphingolipid Metabolism

Erin Morris Richard; Thirumagal Thiyagarajan; Marlene A. Bunni; Fahmin Basher; Patrick O. Roddy; Leah J. Siskind; Paul J. Nietert; Tamara K. Nowling

doi:10.1371/journal.pone.0075175

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Peer-reviewed

Research Article

Reducing FLI1 Levels in the MRL/lpr Lupus Mouse Model Impacts T Cell Function by Modulating Glycosphingolipid Metabolism

Erin Morris Richard,

Current address: Hollings Science Center, College of Charleston, Charleston, South Carolina, USA

Affiliation Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Thirumagal Thiyagarajan,

Affiliation Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Marlene A. Bunni,

Affiliation Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Fahmin Basher,

Affiliation Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Patrick O. Roddy,

Affiliation Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Leah J. Siskind,

Current address: Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, USA

Affiliations Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America, Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, United States of America
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Paul J. Nietert,

Affiliation Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of America
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Tamara K. Nowling

* E-mail: nowling@musc.edu

Affiliations Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America, Research Service, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, United States of America
⨯

Reducing FLI1 Levels in the MRL/lpr Lupus Mouse Model Impacts T Cell Function by Modulating Glycosphingolipid Metabolism

Erin Morris Richard,
Thirumagal Thiyagarajan,
Marlene A. Bunni,
Fahmin Basher,
Patrick O. Roddy,
Leah J. Siskind,
Paul J. Nietert,
Tamara K. Nowling

Published: September 10, 2013
https://doi.org/10.1371/journal.pone.0075175

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