Alterations in Regulatory T Cells Induced by Specific Oligosaccharides Improve Vaccine Responsiveness in Mice

Marcel A. Schijf; JoAnn Kerperien; Jacqueline Bastiaans; Kirsten Szklany; Jenny Meerding; Gerard Hofman; Louis Boon; Femke van Wijk; Johan Garssen; Belinda van’t Land

doi:10.1371/journal.pone.0075148

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Open Access

Peer-reviewed

Research Article

Alterations in Regulatory T Cells Induced by Specific Oligosaccharides Improve Vaccine Responsiveness in Mice

Marcel A. Schijf,

Affiliations Department of Pediatric Immunology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Immunology, Nutricia Research, Utrecht, The Netherlands
⨯
JoAnn Kerperien,

Affiliation Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands
⨯
Jacqueline Bastiaans,

Affiliations Department of Immunology, Nutricia Research, Utrecht, The Netherlands, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands
⨯
Kirsten Szklany,

Affiliation Department of Immunology, Nutricia Research, Utrecht, The Netherlands
⨯
Jenny Meerding,

Affiliation Department of Pediatric Immunology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Gerard Hofman,

Affiliation Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands
⨯
Louis Boon,

Affiliation Bioceros, Utrecht, The Netherlands
⨯
Femke van Wijk,

Affiliation Department of Pediatric Immunology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
⨯
Johan Garssen,

Affiliations Department of Immunology, Nutricia Research, Utrecht, The Netherlands, Utrecht Institute for Pharmaceutical Sciences (UIPS), Utrecht University, Utrecht, The Netherlands
⨯
Belinda van’t Land

* E-mail: b.vantland@umcutrecht.nl

Affiliations Department of Pediatric Immunology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Immunology, Nutricia Research, Utrecht, The Netherlands
⨯

Alterations in Regulatory T Cells Induced by Specific Oligosaccharides Improve Vaccine Responsiveness in Mice

Marcel A. Schijf,
JoAnn Kerperien,
Jacqueline Bastiaans,
Kirsten Szklany,
Jenny Meerding,
Gerard Hofman,
Louis Boon,
Femke van Wijk,
Johan Garssen,
Belinda van’t Land

Published: September 20, 2013
https://doi.org/10.1371/journal.pone.0075148

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