Synergistic Re-Activation of Epigenetically Silenced Genes by Combinatorial Inhibition of DNMTs and LSD1 in Cancer Cells

• Han Han ,

  Contributed equally to this work with: Han Han, Xiaojing Yang

  Affiliations Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy,University of Southern California, Los Angeles, California, United States of America, Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern, California, Los Angeles, California, United States of America

  ⨯
• Xiaojing Yang ,

  Contributed equally to this work with: Han Han, Xiaojing Yang

  Affiliation Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern, California, Los Angeles, California, United States of America

  ⨯
• Kurinji Pandiyan,

  Affiliations Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern, California, Los Angeles, California, United States of America, Program in Human Genetics, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Gangning Liang

  * E-mail: gliang@usc.edu

  Affiliation Departments of Urology and Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern, California, Los Angeles, California, United States of America

  ⨯