Signaling via Class IA Phosphoinositide 3-Kinases (PI3K) in Human, Breast-Derived Cell Lines

Veronique Juvin; Mouhannad Malek; Karen E. Anderson; Carine Dion; Tamara Chessa; Charlotte Lecureuil; G. John Ferguson; Sabina Cosulich; Phillip T. Hawkins; Len R. Stephens

doi:10.1371/journal.pone.0075045

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Open Access

Peer-reviewed

Research Article

Signaling via Class IA Phosphoinositide 3-Kinases (PI3K) in Human, Breast-Derived Cell Lines

Veronique Juvin,

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Mouhannad Malek,

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Karen E. Anderson,

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Carine Dion,

Current address: Naturalpha, Parc Eurasanté, Loos, France

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Tamara Chessa,

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Charlotte Lecureuil,

Current address: Institut de Recherche sur la Biologie de l’Insecte, Unite Mixte de Recherche, Centre National Recherche Scientifique 6035, Université F. Rabelais, Tours, France

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
G. John Ferguson,

Current address: MedImmune, Great Abington, Cambridge, United Kingdom

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Sabina Cosulich,

Current address: Novatis Institute for Biomedical Research, Oncology Disease Area, Novartis Pharma AG, Basel, Switzerland

Affiliations The Babraham Institute, Babraham, Cambridge, United Kingdom, Astrazeneca, Macclesfield United Kingdom
⨯
Phillip T. Hawkins ,

Contributed equally to this work with: Phillip T. Hawkins, Len R. Stephens

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯
Len R. Stephens

Contributed equally to this work with: Phillip T. Hawkins, Len R. Stephens

* E-mail: len.stephens@babraham.ac.uk

Affiliation The Babraham Institute, Babraham, Cambridge, United Kingdom
⨯

Signaling via Class IA Phosphoinositide 3-Kinases (PI3K) in Human, Breast-Derived Cell Lines

Veronique Juvin,
Mouhannad Malek,
Karen E. Anderson,
Carine Dion,
Tamara Chessa,
Charlotte Lecureuil,
G. John Ferguson,
Sabina Cosulich,
Phillip T. Hawkins,
Len R. Stephens

Published: October 4, 2013
https://doi.org/10.1371/journal.pone.0075045

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Phosphorylation
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Chemotaxis
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RNA interference
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Breast cancer
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Membrane proteins
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Tyrosine kinases
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Lipid signaling
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