Sphingosine Kinase 1 Serves as a Pro-Viral Factor by Regulating Viral RNA Synthesis and Nuclear Export of Viral Ribonucleoprotein Complex upon Influenza Virus Infection

Open Access

Peer-reviewed

Research Article

Young-Jin Seo,

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Curtis J. Pritzl,

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Madhuvanthi Vijayan,

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Kavita Bomb,

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Mariah E. McClain,

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Stephen Alexander,

Affiliation Division of Biological Sciences, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Bumsuk Hahm

* E-mail: hahmb@health.missouri.edu

Affiliation Departments of Surgery & Molecular Microbiology and Immunology, University of Missouri-Columbia, Columbia, Missouri, United States of America
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Influenza viruses
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Influenza
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Transcription factors
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MAPK signaling cascades
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Ribonucleoproteins
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Viral replication
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ERK signaling cascade
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Small interfering RNA
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