Helicobacter pylori Infection Synergizes with Three Inflammation-Related Genetic Variants in the GWASs to Increase Risk of Gastric Cancer in a Chinese Population

Miao Li; Liu Huang; Hong Qiu; Qiang Fu; Wen Li; Qianqian Yu; Li Sun; Lihong Zhang; Guangyuan Hu; Junbo Hu; Xianglin Yuan

doi:10.1371/journal.pone.0074976

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Open Access

Peer-reviewed

Research Article

Helicobacter pylori Infection Synergizes with Three Inflammation-Related Genetic Variants in the GWASs to Increase Risk of Gastric Cancer in a Chinese Population

Miao Li,

Current address: Department of Oncology, Central Hospital of Wuhan, Wuhan, Hubei Province, China

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Liu Huang,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Hong Qiu,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Qiang Fu,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Wen Li,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Qianqian Yu,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Li Sun,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Lihong Zhang,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Guangyuan Hu,

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Junbo Hu,

Affiliation Department of Surgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯
Xianglin Yuan

* E-mail: yxl@medmail.com.cn

Affiliation Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
⨯

Helicobacter pylori Infection Synergizes with Three Inflammation-Related Genetic Variants in the GWASs to Increase Risk of Gastric Cancer in a Chinese Population

Miao Li,
Liu Huang,
Hong Qiu,
Qiang Fu,
Wen Li,
Qianqian Yu,
Li Sun,
Lihong Zhang,
Guangyuan Hu,
Junbo Hu

Published: September 19, 2013
https://doi.org/10.1371/journal.pone.0074976

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Helicobacter pylori
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Cancer risk factors
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Single nucleotide polymorphisms
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Variant genotypes
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Inflammation
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Genome-wide association studies
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Gastric cancer
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