The Contribution of Orai(CRACM)1 and Orai(CRACM)2 Channels in Store-Operated Ca2+ Entry and Mediator Release in Human Lung Mast Cells

Open Access

Peer-reviewed

Research Article

The Contribution of Orai(CRACM)1 and Orai(CRACM)2 Channels in Store-Operated Ca²⁺ Entry and Mediator Release in Human Lung Mast Cells

Ian Ashmole,

Affiliation Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Glenfield Hospital, Leicester, Leicestershire, United Kingdom
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S. Mark Duffy,

Affiliation Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Glenfield Hospital, Leicester, Leicestershire, United Kingdom
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Mark L. Leyland,

Affiliation Department of Biochemistry, Henry Wellcome Building, University of Leicester, Leicester, Leicestershire, United Kingdom
⨯
Peter Bradding

* E-mail: pbradding@hotmail.com

Affiliation Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Glenfield Hospital, Leicester, Leicestershire, United Kingdom
⨯

Mast cells
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Cell degranulation
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Adenoviruses
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Luciferase
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Gene expression
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Patch clamp techniques
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Rodents
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Cytokines
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