Cataract-Causing Mutation of Human Connexin 46 Impairs Gap Junction, but Increases Hemichannel Function and Cell Death

Open Access

Peer-reviewed

Research Article

Qian Ren,

Affiliations First Hospital of Lanzhou University, Lanzhou, China, Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Manuel A. Riquelme,

Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Ji Xu,

Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Xiang Yan,

Affiliation First Hospital of Lanzhou University, Lanzhou, China
⨯
Bruce J. Nicholson,

Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Sumin Gu,

Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯
Jean X. Jiang

* E-mail: jiangj@uthscsa.edu

Affiliation Department of Biochemistry, University of Texas Health Science Center, San Antonio, Texas, United States of America
⨯

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Gap junctions
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HeLa cells
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Transfection
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Cataracts
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Eye lens
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Apoptosis
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Membrane proteins
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Computer software
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