PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1

Courtney Nicholas; Jennifer Yang; Sara B. Peters; Matthew A. Bill; Robert A. Baiocchi; Fengting Yan; Saïd Sïf; Sookil Tae; Eugenio Gaudio; Xin Wu; Michael R. Grever; Gregory S. Young; Gregory B. Lesinski

doi:10.1371/journal.pone.0074710

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Open Access

Peer-reviewed

Research Article

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27^Kip1

Courtney Nicholas,

Affiliation Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Jennifer Yang,

Affiliation Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Sara B. Peters,

Affiliation Department of Pathology, Division of Dermatopathology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Matthew A. Bill,

Affiliation Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Robert A. Baiocchi,

Affiliation Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Fengting Yan,

Affiliation Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Saïd Sïf,

Affiliation Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Sookil Tae,

Affiliation Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
⨯
Eugenio Gaudio,

Affiliation Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America
⨯
Xin Wu,

Affiliation The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Michael R. Grever,

Affiliation Department of Internal Medicine, Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯
Gregory S. Young,

Affiliation Center for Biostatistics, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, Ohio, United States of America
⨯
Gregory B. Lesinski

* E-mail: Gregory.Lesinski@osumc.edu

Affiliation Department of Internal Medicine, Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America
⨯

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27^Kip1

Courtney Nicholas,
Jennifer Yang,
Sara B. Peters,
Matthew A. Bill,
Robert A. Baiocchi,
Fengting Yan,
Saïd Sïf,
Sookil Tae,
Eugenio Gaudio,
Xin Wu

Published: September 30, 2013
https://doi.org/10.1371/journal.pone.0074710

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